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How does Estrace compare to Premarin? Estrace vaginal cream (Estradiol vaginal cream) works well to treat menopausal symptoms localized to the vagina. Relieves vaginal dryness and pain during sex due to menopause. Premarin vaginal cream (conjugated estrogens) has less side-effects than estrogen pills, but only works for localized symptoms of menopause.
What are the disadvantages of hormone replacement therapy? A disadvantage of hormone replacement therapy is an increased risk of forming gall-bladder stones and undergoing cholecystectomy. Unopposed estrogen therapy gives a higher incidence of endometrial cancer in women with an intact uterus, but the contribution of progestins for about 10 days every month excludes this risk.
Do you need hormone replacement after a total hysterectomy? The procedure is often combined with a hysterectomy -- removal of the uterus -- but not always. And in fact, women who only have their uterus removed will not go into surgical menopause. Their ovaries are still making estrogen.
Can you take HRT for the rest of your life? Stopping HRT There's no limit on how long you can take HRT, but talk to your GP about the duration of treatment they recommend. Most women stop taking it once their menopausal symptoms pass, which is usually after a few years. You may need to start HRT again.
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